- Computational design and development of theranostic agents Our group focuses on the design of molecules for customized applications followed by their chemical synthesis using organic reactions and testing. Currently, molecular systems are being developed for medical applications with a special emphasis on theranostic applications.
- Combinatorial chemistry, drug discovery and drug delivery The principles, tools and techniques of combinatorial chemistry are being explored by our group to develop novel molecular entities centred around heterocyclic cores to enhance molecular diversity. The libraries are initially screened using docking studies employing cancer biomarkers and promising systems are chemically synthesized and tested for anticancer activities followed by protein binding studies. For targeted drug delivery, we currently employ dendrimers.
- Self assembled molecular architectures Self-assembly of molecules into well-defined nanostructures with controlled size, morphology and optical properties is a challenging task in the “bottom-up” construction of supramolecular architectures. Herein our department, we are focusing on the development of self-assembled molecular architectures from bioresources and controlling the self–assembly via concerted action of noncovalent interactions. These self-assembled architectures have potential uses in molecular devices, stimuli responsive materials, solar cells etc.
Department